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You are here: Contents > 2010 > Volume 19 Number 6 November 2010 > AORTIC VALVE DISEASE > Predictors for Late Insufficiency of the Neo-Aortic Valve after the Switch Procedure

Predictors for Late Insufficiency of the Neo-Aortic Valve after the Switch Procedure

Xiangbin Pan, Shengshou Hu, Shoujun Li, Zhe Zheng, Yang Wang, Yajuan Zhang, Xin Yuan, Yan Li 

Department of Cardiovascular Surgery, Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China

Background and aim of the study: The study aim was to investigate the mid-term risk factors for neo-aortic regurgitation in patients with transposition of the great arteries (TGA) and Taussig-Bing malformation after the arterial switch operation (ASO).
Methods: Between February 2001 and December 2007, a total of 202 patients with TGA or Taussig-Bing malformation underwent the ASO at the authors’ institution. Subsequently, 185 surviving patients (140 males, 45 females; mean age 14 ± 28 months) were followed up in the out-patient department, using echocardiography. A multiple logistic regression analysis was performed to identify the risk factors for postoperative neo-aortic regurgitation.
Results: The mean period of follow up was 35 ± 22 months (range: 3 to 88 months). Postoperative neo-aortic regurgitation was present in 19 patients; this

was mild in 16 cases (9%) and moderate in three (2%). During the follow up, freedom from aortic regurgitation was 90%; the overall rates of freedom from aortic regurgitation at one, three, and five years were 95%, 89%, and 83%, respectively. The mid-term risk factors for neo-aortic regurgitation were ventricular septal defect (VSD) (p = 0.02), operative age >6 months (p = 0.01), and a postoperative neo-aortic valve Z-score >1 (p <0.01).
Conclusion: The ASO showed an acceptable mid-term function of the aortic valve. The risk factors for postoperative neo-aortic regurgitation included VSD, operative age >6 months, and a postoperative neo-aortic valve Z-score >1.


The Journal of Heart Valve Disease 2010;19:731-735

Predictors for Late Insufficiency of the Neo-Aortic Valve after the Switch Procedure

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