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You are here: Contents > 2012 > Volume 21 Number 4 July 2012 > MISCELLANEOUS > Lipid Insudation as a Cause of Structural Failure of a Stentless Pericardial Bioprosthesis

Lipid Insudation as a Cause of Structural Failure of a Stentless Pericardial Bioprosthesis

Giacomo Ravenni, Stefano Pratali, Mila Della Barbera, Marialuisa Valente, Gaetano Thiene, Uberto Bortolotti

Section of Cardiac Surgery, Cardiac Thoracic and Vascular Department, University of Pisa Medical School, Pisa, Department of Medical-Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy

The Sorin Pericarbon Freedom (SPF) valve is a stentless bioprosthesis made from bovine pericardium, with a peculiar design aimed at preventing the mechanical failures observed with old models of stented pericardial bioprostheses. Herein, the case is described of a patient who presented with severe regurgitation of a SPF six years after aortic valve replacement, caused by commissural dehiscence. Both, microradiographic

and histologic investigations, revealed mild calcific deposits and massive lipid infiltration, thus confirming that a patient-related mechanism such as ‘atheromasia’ can account for structural valve deterioration also in recipients of pericardial bioprostheses.


The Journal of Heart Valve Disease 2012;21:509-512

Lipid Insudation as a Cause of Structural Failure of a Stentless Pericardial Bioprosthesis

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