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You are here: Contents > 2013 > Volume 22 Number 5 September 2013 > MITRAL VALVE DISEASE > Long-Term Results of Surgical Correction for Mitral Paravalvular Leak: Repair versus Re-Replacement

Long-Term Results of Surgical Correction for Mitral Paravalvular Leak: Repair versus Re-Replacement

Jae-woong Choi, Ho Young Hwang, Kyung-Hwan Kim, Ki-Bong Kim, Hyuk Ahn

Seoul National University Hospital, Jongno-gu, Seoul, Korea

Background and aim of the study: Paravalvular leak (PVL) is a common clinical manifestation after cardiac valve replacement. The results of surgical management for mitral PVL were evaluated and compared according to the surgery employed.

Methods: Between September 1995 and September 2009, a total of 52 patients (30 males, 22 females; mean age 57.2 ± 13.0 years) underwent surgery for mitral PVL. Thirty-five patients (67.3%) underwent multiple cardiac surgeries more than once. PVL was treated with leak site repair in 22 patients (group I) and re-replacement of the mitral valve in 30 patients (group II). Concomitant operations were performed in 34 patients (65.4%). The mean duration of follow up was 57.4 ± 39.4 months.

Results: There were six (11.5%) in-hospital deaths. Postoperative complications occurred in 19 patients, including low cardiac output syndrome (n = 7). There were no differences in early results between the two groups. The presence of more than moderate tricuspid

regurgitation was the only risk factor for in-hospital mortality to reach statistical significance (p = 0.023). During the follow up period, late death occurred in 11 patients, including four cardiac deaths. The 10-year overall survival rate was 57.8%, without intergroup difference (p = 0.699). PVL recurred in 10 patients; the mean rate of freedom from recurrence of PVL was 67.7% at 10 years, and the five- and 10-year major valve-related event-free survival rates were 55.5% and 31.8%, respectively. There were no differences in freedom from recurrence of PVL (p = 0.346) and valve-related event-free survival (p = 0.824) between the two groups.

Conclusion: The surgical treatment of mitral PVL proved to be acceptable when considering the high-risk profile of the patients. However, because of the similar outcomes after leak site repair and re-replacement, a more effective method might be selected on an individual basis when considering the surgical correction of mitral PVL.

The Journal of Heart Valve Disease 2013;22:682-687


Long-Term Results of Surgical Correction for Mitral Paravalvular Leak: Repair versus Re-Replacement

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