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You are here: Contents > 2016 > Volume 25 Number 1 January 2016 > INFECTIVE ENDOCARDITIS > Not So EASE-Y: How Often do Hospitalized Infective Endocarditis Patients Meet Criteria for Early Surgery?

Not So EASE-Y: How Often do Hospitalized Infective Endocarditis Patients Meet Criteria for Early Surgery?

Mohammad Amin Kashef1,2, Auras R. Atreya1,2, Jaime Hernandez-Montfort1,2, Jennifer Friderici2,3, Tara Lagu2,4,5

1Division of Cardiovascular Disease, Baystate Medical Center, Springfield, MA, 2Tufts University School of Medicine, Department of Medicine, MA, 3Division of Academic Affairs, Baystate Medical Center, Springfield, MA, 4Division of Hospital Medicine, Department of Medicine, Baystate Medical Center, Springfield, MA, 5Center for Quality of Care Research, Baystate Medical Center, Springfield, MA, USA

Infective endocarditis (IE) has historically caused significant morbidity and mortality. Valve surgery reduces systemic embolization and mortality, but the optimal timing is controversial. The EASE (Early Surgery Versus Conventional Treatment for Infective Endocarditis) trial, which employed strict inclusion and exclusion criteria, showed that early surgery could reduce the risk of embolic events for a subset of patients. The aim of the present study was to determine

the proportion of adult IE patients seen in usual clinical practice at a single tertiary medical center that would meet EASE enrollment criteria. Over a four-year period, only 10 of 88 patients (11.3%) were found to meet EASE enrollment criteria. These results have important research implications, and highlight the differences between populations of patients used in clinical trials and patients seen in practice.

The Journal of Heart Valve Disease 2016;25:72-74

Not So EASE-Y: How Often do Hospitalized Infective Endocarditis Patients Meet Criteria for Early Surgery?

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