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You are here: Contents > 2016 > Volume 25 Number 3 May 2016 > MITRAL VALVE DISEASE > MitraClip®: Two Weeks after Implantation

MitraClip®: Two Weeks after Implantation

Juliëtte F. Velu1, Hans H. de Boer2, Berto J. Bouma1, Jan Baan (Jr)1,3

1Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands
2Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands
3Electronic correspondence: j.baan@amc.nl

A 73-year-old male received a percutaneous mitral valve repair with a MitraClip to treat severe (grade IV) symptomatic mitral regurgitation (MR). The MitraClip® procedure reduced the MR to grade I, but the patient died 14 days post-procedurally due to a pneumosepsis. Histological analysis of the MitraClip mesh covering

showed a chronic inflammatory reaction with an abundance of multinucleated giant cells. Remarkably, signs of early onset clip-coverage were found, indicated by the presence of a few scattered myofibroblasts.

The Journal of Heart Valve Disease 2016;25:320-322


MitraClip®: Two Weeks after Implantation

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