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You are here: Contents > 2016 > Volume 25 Number 6 November 2016 > CASE REPORT > Multiple Valvular Complications of Hypereosinophilic Syndrome

Multiple Valvular Complications of Hypereosinophilic Syndrome

Zoltán Pozsonyi1,2,3, Szabolcs Benedek1, Pál Sármán1, Lívia Jánoskuti1, Tivadar Hüttl2, Astrid Apor2

13rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
2Heart Center, Semmelweis University, Budapest, Hungary
3Electronic correspondence: pozsonyizoltanimre@gmail.com

Endomyocardial fibrosis (EMF) is the most common cardiac abnormality in hyeperosinophilic syndrome (HES), sometimes complicated with mitral valve disease. Mitral valve disease without ventricular manifestation is very rare, however. Case reports link HES to prosthetic valve thrombosis (PVT), but the optimal type of prosthetic valve in HES is not known. Herein is reported the case of a young female HES patient with secondary mitral valve degeneration and severe regurgitation. A mechanical prosthetic valve was implanted six months after she was diagnosed with HES, but despite anticoagulation and

 

antiplatelet therapy she developed PVT three months later. Partially successful thrombolysis was followed by biological prosthetic valve implantation, with no further complications during the subsequent four years. The eosinophil count and treatment for HES was basically unchanged during the follow up period, following the initiation of treatment. Based on these findings it is suggested that, in HES, the implantation of a biological prosthetic valve might be preferable over a mechanical valve.

The Journal of Heart Valve Disease 2016;25:752-755

Multiple Valvular Complications of Hypereosinophilic Syndrome

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