Warfarin-Induced Skin Necrosis and Heparin-Induced Thrombocytopenia following Mitral Valve Replacement for Marantic Endocarditis Craig A. White, Darryl A. Chung, Martyn Thomas, Michael T. Marrinan |
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Hemostatic physiology involves a complex interlinking of blood and endothelial factors. Its pharmacological manipulation invariably impacts at multiple molecular sites. Herein is reported an unusual case of coexistent warfarin-induced skin necrosis and heparin-induced thrombocytopenia following mitral valve replacement |
for thromboembolic phenomena associated with marantic
endocarditis and bronchial adenocarcinoma. Thrombophilia in the face
of endocarditis should be treated with a suspicion of underlying cancer. |
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