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Influence of HLA Matching and Associated Factors on Aortic Valve
Homograft Function
Rebecca Dignan MD, Mark O’Brien FRCS, Patrick Hogan FRCPA, Jurgen Passage, Fiona Stephens B Appl Sci, Alycia Thornton BSc, Susan Harrocks RN The association between aortic valve homograft dysfunction and human leukocyte antigen DR mismatch suggests that elements of the anti-donor immune response penetrate and damage the aortic valve homograft. A similar link to postoperative fever indicates that immune stimulation may be an early event. |
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