Characterization of the severity of aortic stenosis relies on accurate measurement of the pressure drop across the valve. Transvalvular pressure drops obtained by Doppler ultrasound typically overestimate gold standard measurements performed during cardiac catheterization. Sources of discrepancy between the Doppler and catheter measurements have been identified, but no method has been developed to reconcile fully the two techniques. In this study we develop a correction to the clinical form of the Bernoulli equation based on receiving chamber geometry and turbulent jet profiles. This was applied in a unique clinical study to Doppler and catheter data obtained simultaneously in patients with aortic valve disease. The results demonstrate the ability to characterize Doppler/catheter discrepancies based on predicted pressure recovery location, and have implications for optimal pressure sensor placement for the assessment of aortic stenosis and also for the evaluation of prosthetic heart valves in vitro