Aortic Valve Replacement in a Patient with Factor XII Deficiency: Case Report
Tadahiro Murakami MD, Toshihiko Shibata MD, Yasuyuki Sasaki MD, Mitsuharu Hosono MD, Shigefumi Suehiro MD, Hiroaki Kinoshita MD

Aortic valve replacement (AVR) in a patient with factor XII deficiency is described. On admission, the patientŐs activated partial thromboplastin time (aPTT) was prolonged (271 s), and activated clotting time was 500 s. His factor XII level was <3%. AVR was performed safely after the normalization of aPTT and Sonoclot® signature by frozen plasma transfusion.