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Clinical and Hemodynamic Performance of the Toronto SPV Bioprosthesis
Mark H. Danton FRCS, Masim A. Sarsam FRCS, John G. Byrne MD, Norman S. Campbell FRCP, J. Mark Jones FRCS, Gianfranco Campalani MD Advanced age and presence of ischemic heart disease increases mortality following aortic valve replacement (AVR). Over a four-year period, 123 predominantly elderly patients underwent AVR using the Toronto SPV. Despite advanced age (median 72 years) and high concomitant procedure rate (49%), the early mortality rate was low (0.8%). Mean (± SD) actuarial survival at 53 months was 78 ± 5.9%, with most patients in NYHA classes I and II. Serial Doppler echocardiography revealed excellent effective orifice areas with low transvalvular gradients (8.8 ± 4.3 mmHg) for all valve sizes. Left ventricular end-systolic dimensions and fractional shortening improved significantly during the study period. We conclude that the Toronto SPV is an appropriate choice for patients who are elderly and/or require concomitant procedures. In addition to the low operative mortality and excellent functional outcome, the superior hemodynamic profile resulted in left ventricular function improvement. |
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