Double Valve Replacement in a Patient with Osteogenesis Imperfecta
Balakrishnan Mahesh FRCS, Stephen Evans FRCP, Alan J. Bryan FRCS

Valvular heart disease (predominantly aortic and mitral valve disease) has been well documented in patients with osteogenesis imperfecta. Twenty-two prior reports of valve replacement and/or repair have been published. Mortality from cardiac surgery in these patients has been high, particularly in those receiving dual valve prostheses. Here, a patient is described with advanced cardiovascular disease who underwent successful aortic and mitral valve replacement. This represents the second reported survival of double valve replacement in osteogenesis imperfecta and a reduced mortality rate for this procedure.