Share this page on LinkedIn
Share This Page on Google+
Share This Page on Twitter
tell someone about this page print this page
You are here: Contents > 2004 > Volume 13 Number 6 November 2004 > AORTIC VALVE DISEASE > Determinants of Health-related Quality of Life after Aortic Valve Replacement in Six-Month Survivors of Intervention

Determinants of Health-related Quality of Life after Aortic Valve Replacement in Six-Month Survivors of Intervention

Henning T. Baberg, Matthias Dirlich, Axel Laczkovics, Peter Grewe, Waldemar Bojara, Justus de Zeeuw, Torsten T. Bauer, Joachim Kugler, Andreas Mügge
Medical Clinic II, Cardiology and Angiology, Clinic of Cardiac and Thoracic Surgery, Medical Clinic III, Pneumology, Allergology and Sleep Medicine, University Hospital Bergmannsheil, Bochum, Germany, Department of Biomathematics and Statistics, Technical University, Dresden, Germany

Background and aim of the study: Although several determinants of survival after aortic valve replacement (AVR) have been identified, current knowledge regarding factors influencing the postoperative quality of life (QoL) is poor. The study aim was to evaluate health-related QoL (using Medical Outcome Study Short Form-36) in six-month survivors after AVR, and to determine predictors of outcome.
Methods: All patients undergoing heart valve surgery at the authors’ hospital between 1992 and May 1999 were included. Data from 201 patients (119 males, 82 females; mean age 66.6 years) after AVR were obtained. The mean observation period was 42.5 months.
Results: Patients in preoperative NYHA classes I and II had a postoperative QoL comparable to that of the general population, while subjects in NYHA classes III and IV scored significantly lower. Multivariate

analysis identified four independent predictors (preoperative NYHA class, diabetes mellitus, prosthetic valve type, sternal complications) for the Physical component score. NYHA class, atrial fibrillation, sternal complications and type of valvular heart disease were predictors for the Mental component score. No correlation was found between preoperative left ventricular function or size, pre-existing coronary artery disease or prior myocardial infarction and the postoperative QoL.
Conclusion: Notably, preoperative aortic stenosis was identified as a strong and independent predictor of the postoperative QoL in six-month survivors after AVR. This effect was independent of left ventricular size and function. These findings support the proposal that patients with aortic stenosis should be operated on at an earlier stage, if possible before they develop symptoms.
The Journal of Heart Valve Disease 2004;13:914-920

Determinants of Health-related Quality of Life after Aortic Valve Replacement in Six-Month Survivors of Intervention

Click the above hyperlink to view the article, right click (Ctrl click on a Mac) to open in a new browser window or tab.

Purchase this Article

Please click the button below to purchase this article. Single article purchases are provided at $50.00 per article. Upon clicking the button below, single article user account subscription details are requested and, upon successful payment, a single article user account is created. Single articles are availble in your account for seven days after purchase.