AORTIC VALVE DISEASE

Progression of Aortic Valve Stenosis in Adults: A Systematic Review Helena J. Heuvelman, Martijn W. A. van Geldorp, Marinus J. C. Eijkemans, Nalini M. Rajamannan, Ad J. J. C. Bogers, Jolien W. Roos-Hesselink, Johanna J. M. Takkenberg	454
Rosuvastatin Slows the Development of Diastolic Dysfunction in Calcific Aortic Stenosis Luis M. Moura,Sandra F. Ramos, Steen D. Kristensen, Fausto J. Pinto, Isabel M. Barros, Francisco Rocha-Gonçalves	463
Editorial Aldosterone Antagonists and Chronic Aortic Regurgitation: Promising But Not Quite Ready for Prime Time Luis M. Moura, F. Rocha-Gonçalves, Robert W. Emery	473
Editorial: Potentially Modifiable Biological Targets in Aortic Regurgitation Ajit D. Pai, Ramdas G. Pai	476
Effects of Spironolactone Treatment on an Experimental Model of Chronic Aortic Valve Regurgitation Adnane Zendaoui, Dominic Lachance, Élise Roussel, Jacques Couet, Marie Arsenault	478
Urgent Aortic Valve Replacement in Octogenarians: Does an ‘Urgent’ Status Increase Morbidity and Mortality? Changyong Yang, Dadong Li, Roger Mennett, Jonathan Hammond2, Gong Zhang, Donghui Chen, Robert Gallagher	487
An Automated Coring and Apical Connector Insertion Device Facilitates Aortic Valve Bypass (Apicoaortic Conduit) Surgery: Preclinical Experience in a Chronic Ovine Model James S. Gammie, John W. Brown, J. Alan Crunkleton, Gregory J. Bittle1, Craig E. Stauffer, Anthony G. Liepert, Mehrdad Ghoreishi	494