Suleyman Ercan1, Gokhan Altunbas2, Vedat Davutoglu1, Fethi Yavuz1, Okkeş Uku3, Fuat Basanalan1, Mehmet Kaplan1, Hayri Alici1
1Department of Cardiology, Gaziantep University, School of Medicine, Gaziantep, 2Department of Cardiology, Kilis State Hospital, Kilis, 3Department of Cardiology, Balikligol State Hospital, Şanlıurfa, Turkey
Background and aim of the study: Although mitral stenosis has profound effects on the circulation and hemodynamics, few data exist regarding its impact on aortic elastic properties. The study aim was to determine the association between mitral stenosis and aortic elastic properties by using strain and distensibility as a surrogate.
Methods: Sixty-six patients with echocardiographic documentation of rheumatic mitral stenosis, and 25 age- and gender-matched healthy control subjects were enrolled in the study. Aortic elasticity parameters including strain and distensibility were measured by means of echocardiography.
Results: The mean age of the patient and control groups were 41.8 ± 12.0 and 38.9 ± 5.0 years, respectively (p = 0.12). There was a significant impairment in distensibility
and strain in the patient group compared to controls (0.276 ± 0.167 versus 0.491 ± 0.260 cm2.dyn-1, p = 0.001; 6.54 ± 3.18% versus 9.19 ± 4.78%, p = 0.015). There was a strong correlation between distensibility and left atrial diameter (p <0.001; r = -0.39), left atrial volume index (p <0.001; r = -0.56), mitral valve area (p <0.001; r = 0.40), and mean transmitral gradient (p = 0.022; r = -0.18). Strain was also associated with left atrial diameter (p = 0.002; r = -0.32), left atrial volume index (p <0.001; r = -0.41), mitral valve area (p = 0.002; r = 0.31), and mean transmitral gradient (p = 0.035; r = -0.18).
Conclusion: Mitral stenosis was shown to be associated with impaired aortic elasticity, but further studies are required to clarify the clinical significance of this finding.
The Journal of Heart Valve Disease 2013;22:550-555
|Impact of Rheumatic Mitral Stenosis on Aortic Elastic Properties|
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