Share this page on LinkedIn
Share This Page on Google+
Share This Page on Twitter
tell someone about this page print this page
You are here: Contents > 2014 > Volume 23 Number 2 March 2014 > MITRAL VALVE DISEASE > Recurrent Native and Prosthetic Mitral Valve Thrombosis in Idiopathic Hypereosinophilic Syndrome

Recurrent Native and Prosthetic Mitral Valve Thrombosis in Idiopathic Hypereosinophilic Syndrome

Lilia Zakhama, Iskander Slama, Elhem Boussabah, Basma Harbegue, Majdi Mimouni, Nabil Abdelaali, Sana Sioua, Moez Thameur, Soraya Benyoussef

Cardiology Department, FSI Hospital, La Marsa, Tunis, Tunisia

Hypereosinophilic syndrome (HES) is defined as a prolonged, unexplained peripheral eosinophilia. Endomyocardial fibrosis and mural thrombus formation are common occurrences such that patients are exposed to lethal thromboembolic complications. The valvular damage described is mainly related to iterative valve thromboses that are amenable to surgery. Here, the case is reported of a 39-year-old woman suffering from HES with mitral valve thrombosis and mechanical prosthetic mitral valve replacement, in whom a new thrombosis of the inserted prosthesis occurred one month postoperatively, 

concomitant with severe hypereosinophilia and despite adequate anticoagulation. The patient had received a new bioprosthetic mitral valve replacement, and her eosinophil count had been normalized after treatment with corticosteroids. Oral anticoagulation with warfarin was maintained. Subsequently, no recurrent thromboembolic events were reported, and echocardiography performed at the one-year follow up showed the bioprosthesis to have a normal hemodynamic profile.

The Journal of Heart Valve Disease 2014;23:168-170

Recurrent Native and Prosthetic Mitral Valve Thrombosis in Idiopathic Hypereosinophilic Syndrome

Click the above hyperlink to view the article, right click (Ctrl click on a Mac) to open in a new browser window or tab.

Purchase this Article

Please click the button below to purchase this article. Single article purchases are provided at $50.00 per article. Upon clicking the button below, single article user account subscription details are requested and, upon successful payment, a single article user account is created. Single articles are availble in your account for seven days after purchase.