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You are here: Contents > 2015 > Volume 24 Number 1 January 2015 > CASE REPORT > Osteopetrosis: A Case of ‘Hostile Chest’ Associated with Symptomatic Aortic Valve Stenosis

Osteopetrosis: A Case of ‘Hostile Chest’ Associated with Symptomatic Aortic Valve Stenosis

Emmanuel Villa1, Giuseppe Lauria1, Antonio Messina1, Andrea Rizzi2, Angela D’Ambrosio3, Ornella Leonzi2, Tony Sabatini4, Giovanni Troise1

Departments of 1Cardiac Surgery, 2Cardiology, 3Radiology and 4Medicine, Poliambulanza Foundation Hospital, Brescia, Italy

Osteopetrosis is a heterogeneous group of heritable conditions in which there is a defect in bone resorption by osteoclasts. It is associated with an increased skeletal mass due to abnormally dense, but brittle, bones. Osteopetrosis varies greatly in severity, and fracture treatment remains a matter of controversy due to altered responses to fixation and the risk of osteomyelitis.  The fate of sternotomy in this condition is unknown, and osteopetrosis could represent a situation of ‘hostile chest’. Here, the case is described of a patient with osteopetrosis and concomitant symptomatic aortic valve stenosis and coronary artery disease.

The Journal of Heart Valve Disease 2015;24:126-129


Osteopetrosis: A Case of ‘Hostile Chest’ Associated with Symptomatic Aortic Valve Stenosis

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