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You are here: Contents > 2015 > Volume 24 Number 5 September 2015 > AORTIC VALVE DISEASE > Intra- and Inter-Observer Reproducibility of Transcatheter Aortic Valve Replacement Planning Measurements by Multidetector Computed Tomography

Intra- and Inter-Observer Reproducibility of Transcatheter Aortic Valve Replacement Planning Measurements by Multidetector Computed Tomography

Ran Heo1, Bríain ó Hartaigh1, Iksung Cho1, Valentina Valenti1, Jonathon Leipsic2, S. Chiu Wong3, Arash Salemi4, Robert M. Minutello3, Geoffrey Bergman3, James K. Min1,5

1Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, USA, 2Division of Cardiology, St. Paul’s Hospital, Vancouver, BC, Canada, 3Division of Cardiology, Department of Medicine, Weill Cornell Medical College, New York, 4Department of Cardiothoracic Surgery, New York-Presbyterian Hospital/Weill Cornell Medical College, New York, 5Departments of Radiology and Medicine, Weill Cornell Medical College, New York, USA

Background and aim of the study: Multidetector computed tomography (MDCT) is widely used for transcatheter aortic valve replacement (TAVR) planning, and its use predicts and prevents complications. To date, the reproducibility of aortoiliofemoral measurements and prediction of fluoroscopic angles for TAVR deployment remain inadequately studied.

Methods: Twenty-five consecutive patients (six males, 19 females; mean age 81.1 years) undergoing pre-procedural evaluation for TAVR were studied for 74 separate variables by MDCT. Two experienced readers made repeated measurements of the diameter and area of the aortic annulus, the aortic root at the level of the sinuses of Valsalva, sinotubular junction, and ascending aorta, and the diameters of peripheral vessels at the level of the distal abdominal aorta, and the iliofemoral arteries. A fluoroscopic angle prediction was obtained for left anterior oblique (LAO) 0°, 20° and 30° projections. Pearson’s correlation coefficient (r) was obtained, and intra-class correlation coefficients and

Bland-Altman plots were generated to examine agreements, respectively.

Results: The mean aortic valve area was 0.7 cm2. Each measurement generally showed good intra- and inter-observer reproducibility. The mean difference between readers was -0.3 mm for mean annular diameter and 3.6 mm2 for annular area. The area-derived diameter showed better reproducibility than the mean diameter (ICC 0.87, 0.84). However, the right coronary artery height showed poor inter-observer agreement (ICC 0.48). Angle predictions for 0°, 20° and 30°-LAO were reproducible within and between readers (ICC 0.68-0.96 and 0.75-0.85). Qualitative assessments were also reliable between readers.

Conclusion: Inter- and intra-observer measurements of the pre-TAVR planning parameters are reliable, with generally a high degree of agreement.

The Journal of Heart Valve Disease 2015;24:560-569


Intra- and Inter-Observer Reproducibility of Transcatheter Aortic Valve Replacement Planning Measurements by Multidetector Computed Tomography

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