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You are here: Contents > 2017 > Volume 26 Number 2 March 2017 > INFECTIVE ENDOCARDITIS > Fungal Endocarditis Due to Aspergillus oryzae: The First Case Reported in the Literature

Fungal Endocarditis Due to Aspergillus oryzae: The First Case Reported in the Literature

Andrea Mazza1,3, Nicola Luciani1, Marco Luciani1, Federico Cammertoni1, Alessia Giaquinto2, Natalia Pavone1, Piergiorgio Bruno1, Massimo Massetti1

1Department of Cardiovascular Sciences, Catholic University of Sacred Heart, Rome, Italy
2Department of Diagnostic and Laboratory Medicine, Catholic University of Sacred Heart, Rome, Italy
3Electronic correspondence: andreamazza83@hotmail.it

Infective endocarditis (IE) is a severe disease with high mortality and morbidity. Prosthetic valve endocarditis is a life-threatening complication which can occur in less than 10% of patients with valve prosthesis. A fungal etiology of IE is rare and accounts for only 2-4% of all case of endocarditis, but is associated with a higher mortality and morbidity. Herein is reported the first case of fungal endocarditis of aortic valve prosthesis due to Aspergillus oryzae in a 67-year-old caucasian man who nine years  previously underwent mitral and aortic valve replacement with mechanical prostheses, and tricuspid annuloplasty for acute IE due to Enterococcus spp. Seven months previously, the patient also underwent a redo cardiac procedure to replace a mitral valve prosthesis with a new mechanical device due to a leakage. Aspergillus oryzae showed impressive growth with strong and unexpected virulence in both local and systemic settings.

The Journal of Heart Valve Disease 2017;26:205-207


Fungal Endocarditis Due to Aspergillus oryzae: The First Case Reported in the Literature

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