Andrea Mazza1,3, Nicola Luciani1, Marco Luciani1, Federico Cammertoni1, Alessia Giaquinto2, Natalia Pavone1, Piergiorgio Bruno1, Massimo Massetti1
1Department of Cardiovascular Sciences, Catholic University of Sacred Heart, Rome, Italy
|Infective endocarditis (IE) is a severe disease with high mortality and morbidity. Prosthetic valve endocarditis is a life-threatening complication which can occur in less than 10% of patients with valve prosthesis. A fungal etiology of IE is rare and accounts for only 2-4% of all case of endocarditis, but is associated with a higher mortality and morbidity. Herein is reported the first case of fungal endocarditis of aortic valve prosthesis due to Aspergillus oryzae in a 67-year-old caucasian man who nine years||previously underwent mitral and aortic valve replacement with mechanical prostheses, and tricuspid annuloplasty for acute IE due to Enterococcus spp. Seven months previously, the patient also underwent a redo cardiac procedure to replace a mitral valve prosthesis with a new mechanical device due to a leakage. Aspergillus oryzae showed impressive growth with strong and unexpected virulence in both local and systemic settings.
The Journal of Heart Valve Disease 2017;26:205-207
|Fungal Endocarditis Due to Aspergillus oryzae: The First Case Reported in the Literature|
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