Advances in Stem Cell Therapy for Heart Valve Regeneration

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Research Article | Volume 25 Issue 1 (, 2019) | Pages 1 - 7

Advances in Stem Cell Therapy for Heart Valve Regeneration

Cioffi G.

Mazzone C.

Barbati G.

Rossi A.

Nistri S.

Ognibeni F.

Tarantini L.

Di Lenarda A.

Faggiano P.

Pulignano G.

Stefenelli C.

de Simone G.

Under a Creative Commons license

Open Access

Received

Feb. 3, 2019

Revised

April 15, 2019

Accepted

Oct. 5, 2019

Published

Dec. 30, 2019

Abstract

Stem cell therapy offers promising potential for heart valve regeneration, presenting an innovative approach to addressing valve-related pathologies and limitations of current prosthetic and bioprosthetic valves. This review explores the recent advancements in stem cell-based strategies for heart valve regeneration, including various stem cell sources, tissue engineering techniques, and preclinical and clinical outcomes. We highlight the challenges and future directions in this rapidly evolving field.

Keywords

Stem cell therapy

Heart valve regeneration

Tissue engineering

Stem cell sources

Regenerative medicine

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