Biological Heart Valve Performance: Insights from Animal Models

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Research Article | Volume 26 Issue 1 (, 2021) | Pages 1 - 6

Biological Heart Valve Performance: Insights from Animal Models

Viktorsson S.A.

Helgason D.

Orrason A.W.

Aspelund T.

Sigurdsson M.I.

Geirsson A.

Gudbjartsson T.

Under a Creative Commons license

Open Access

Received

Jan. 10, 2020

Revised

May 26, 2020

Accepted

Sept. 16, 2020

Published

Dec. 30, 2020

Abstract

Biological heart valves (BHVs) are an important alternative to mechanical valves for patients requiring heart valve replacement. Despite their advantages in terms of biocompatibility and reduced need for anticoagulation, challenges remain in ensuring the long-term durability and optimal function of these valves. Animal models have played a pivotal role in understanding BHV performance and providing insights into their structural integrity, durability, and interaction with host tissues. This article provides a comprehensive review of biological heart valve performance, focusing on the contribution of animal studies to the understanding of valve degeneration, calcification, and hemodynamic function.

Keywords

Biological heart valves

Animal models

Calcification

Durability

Tissue engineering

Hemodynamics

Heart valve replacement

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