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Research Article | Volume 28 Issue 1 (, 2023) | Pages 1 - 5
Exploring the Role of MicroRNAs in Heart Valve Development and Disease
Ruparelia N.
 ,
Panoulas V.F.
 ,
Frame A.
 ,
Sutaria N.
 ,
Ariff B.
 ,
Gopalan D.
 ,
Chukwuemeka A.
 ,
Mikhail G.W.
 ,
Malik I.S.
Under a Creative Commons license
Open Access
Received
Feb. 4, 2022
Revised
June 15, 2022
Accepted
Oct. 12, 2022
Published
Dec. 30, 2022
Abstract

MicroRNAs (miRNAs) are small non-coding RNAs that play critical roles in the regulation of gene expression. In the context of heart valve development and disease, miRNAs have emerged as important regulators of cellular processes, including differentiation, proliferation, and apoptosis. This review explores the roles of various miRNAs in heart valve development and pathology, examining their mechanisms of action, potential as diagnostic biomarkers, and therapeutic targets. We summarize recent findings and discuss future directions for research in this evolving field.

Keywords
MicroRNAs
Heart valve development
Heart valve disease
Gene regulation
Biomarkers
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Journal of Heart Valve Disease
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