Contents
Download PDF
pdf Download XML
263751 Views
67423 Downloads
Share this article
Review Article | Volume 15 Issue 1 (, 2009) | Pages 67 - 72
Fifteen years of clinical and echocardiographic follow up with the carbomedics heart valve
 ,
 ,
 ,
 ,
 ,
 ,
 ,
 ,
1
Montreal Heart Institute, Department of Surgery, Montreal, Quebec, Canada. michel.carrier@icm-mhi.org
Under a Creative Commons license
PMID : -16480014
Published
Jan. 18, 2006
Abstract

Background and aim of the study: Mechanical prostheses are used in young patients, the CarboMedics valve having been the mechanical valve of choice of the present authors during the past 15 years. The study aim was to analyze long-term clinical and echocardiographic results obtained with CarboMedics mechanical valves.

Methods: A total of 2,953 patients underwent valve replacement with the CarboMedics valve between 1988 and 2004 at the Montreal Heart Institute. Patients were prospectively followed at the outpatient valve clinic. Subsequently, 1,004 patients underwent echocardiographic examinations during follow up.

Results: In total, 1,597 patients (mean age 57 +/- 12 years) underwent isolated aortic valve replacement (AVR), 1,043 patients (mean age 59 +/- 10 years) underwent isolated mitral valve replacement (MVR), and 313 patients (mean age 58 +/- 11 years) underwent AVR+MVR. The mean five-, 10- and 15-year actuarial survival rates were 83 +/- 1%, 70 +/- 2% and 62 +/- 3% in AVR patients, 76 +/- 1%, 59 +/- 2% and 40 +/- 14% in MVR patients, and 68 +/- 3%, 51 +/- 4% and 33 +/- 9% in AVR+MVR patients. The mean 15-year freedom from cerebral embolism, hemorrhage and reoperation was 95 +/- 1%, 97 +/- 1% and 95 +/- 1% in AVR patients, 92 +/- 1%, 97 +/- 1% and 93 +/- 1% in MVR patients, and 94 +/- 2%, 93 +/- 2% and 91 +/- 4% in AVR+MVR patients. AVR patients had a mean aortic gradient of 29 +/- 14, 20 +/- 8, 18 +/- 7, 16 +/- 7, 12 +/- 5 and 11 +/- 5 mmHg with 19, 21, 23, 25, 27 and 29 mm prostheses, respectively (p = 0.001). MVR patients had a mean mitral gradient of 5.3 +/- 3, 4.9 +/- 2.2, 4.6 +/- 2, 4.4 +/- 2.9 and 4.9 +/- 1.8 mmHg with 25, 27, 29, 31 and 33 mm prostheses, respectively (p = 0.63).

Conclusion: Patient survival and valve-related complications were satisfactory at 15 years after valve replacement with the CarboMedics valve. Mean aortic gradients were high with the 19-mm aortic prostheses, but all other valve sizes showed good hemodynamic performance, as measured using transthoracic echocardiography.

 

 

 

How to cite: Carrier M, Pellerin M, Basmadjian A, Bouchard D, Perrault LP, Cartier R, Pagé P, Demers P, Hébert Y. Fifteen years of clinical and echocardiographic follow up with the carbomedics heart valve. J Heart Valve Dis. 2006 Jan;15(1):67-72; discussion 72. PMID: 16480014.

Keywords
Recommended Articles
Research Article
Cross Sectional Study on Nutritional Status and Prevalence of Anemia in Rural Adolescents
Published: 26/06/2013
Download PDF
Read Article
Research Article
To Study the Serum Homocysteine Profile Pattern in AMI & Ischaemic Stroke in Young Adults.
...
Published: 30/08/2025
Download PDF
Read Article
Research Article
Incidence, Clinical Profile, Complications and Outcome of Rodenticide Poisoning in Tertiary Care Hospital
...
Published: 26/08/2025
Download PDF
Read Article
Research Article
To Find Out of the Effects of Mother Nutrition Status on Birth Weight, Anthropometric Measurements of Full-Term Newborn
Published: 07/11/2022
Download PDF
Read Article
© Copyright Journal of Heart Valve Disease