Contents
Download PDF
pdf Download XML
90156 Views
32152 Downloads
Share this article
Review Article | Volume 3 Issue 1 (, 1997) | Pages 111 - 116
Glutaraldehyde, gamma-carboxyglutamic acid and calcium in explanted bioprosthetic heart valves
 ,
 ,
 ,
 ,
 ,
1
Biological and Medical Research Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Under a Creative Commons license
PMID : -8162207
Published
Jan. 29, 1994
Abstract

This paper describes the determination of glutaraldehyde, gamma-carboxylglutamic acid (gamma-CGA) and calcium concentrations in nine bioprosthetic heart valves after explantation. The glutaraldehyde and gamma-CGA were determined by high performance liquid chromatography (HPLC) procedures and the calcium by atomic absorption spectrometry. Glutaraldehyde was detectable in only two of these valves at levels of 17% and 2% of that present in an unimplanted valve. The results indicate that there is no correlation between gamma-CGA and calcium deposition, indicating that the gamma-CGA is probably absorbed onto the forming calcium deposit from the circulation and does not contribute to the calcification process, and that the acid hydrolysable glutaraldehyde decreases with time during implantation. There is, however, no correlation between the duration of implantation and the decrease in glutaraldehyde concentration.

 

 

 

How to cite: Hughes, H., Tipton, L. S., Feuchuk, D., Prabhakar, G., Aboul-Enein, H. Y., & Duran, C. M. (1994). Glutaraldehyde, gamma-carboxyglutamic acid and calcium in explanted bioprosthetic heart valves. The Journal of heart valve disease3(1), 111–116.

Keywords
Recommended Articles
Research Article
Cross Sectional Study on Nutritional Status and Prevalence of Anemia in Rural Adolescents
Published: 26/06/2013
Download PDF
Read Article
Research Article
To Study the Serum Homocysteine Profile Pattern in AMI & Ischaemic Stroke in Young Adults.
...
Published: 30/08/2025
Download PDF
Read Article
Research Article
Incidence, Clinical Profile, Complications and Outcome of Rodenticide Poisoning in Tertiary Care Hospital
...
Published: 26/08/2025
Download PDF
Read Article
Research Article
To Find Out of the Effects of Mother Nutrition Status on Birth Weight, Anthropometric Measurements of Full-Term Newborn
Published: 07/11/2022
Download PDF
Read Article
© Copyright Journal of Heart Valve Disease