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Research Article | Volume 30 Issue 8 (August, 2025) | Pages 351 - 354
A study on Inferior Alveolar Nerve
 ,
 ,
1
Oral and Maxillofacial Surgeon, Professor, Daswani Dental College & Research Centre, Kota Rajasthan
2
Post Graduate Student, Department of Anatomy, Government Medical College, Kota
3
Professor, Department of Anatomy, Government Medical College, Kota.
Under a Creative Commons license
Open Access
Received
July 24, 2025
Revised
Aug. 12, 2025
Accepted
Aug. 25, 2025
Published
Aug. 31, 2025
Abstract

Background & Methods: The Inferior Alveolar Nerve (IAN) is a crucial sensory nerve supplying the lower teeth, chin, and lower lip. Understanding its anatomy, clinical relevance, and risk of injury is essential for both patients and dental practitioners, particularly in procedures such as extractions, implants, and local anesthesia administration. This study examines 100 dental patients undergoing mandibular procedures, evaluating the incidence of IAN-related symptoms, diagnostic imaging, and patient outcomes. Emphasis is placed on improving awareness and preventive strategies in routine dental care. Results: The majority of patients (18 out of 22, or 82%) recovered within four weeks. A small number experienced prolonged symptoms, and only one patient showed signs of long-term or unresolved nerve issues. The data suggests that while IAN symptoms are relatively common, they are typically temporary. Conclusion: 22% experienced IAN-related symptoms. Most cases were mild and resolved within weeks. CBCT imaging significantly enhanced procedural safety. Patient awareness and dentist vigilance are critical in reducing nerve injury risk. This article serves as both a clinical resource and educational tool for patients and professionals

Keywords
INTRODUCTION

The Inferior Alveolar Nerve (IAN) is a branch of the mandibular nerve (V3), the third division of the trigeminal nerve (cranial nerve V). It enters the mandibular foramen, runs through the mandibular canal, and exits through the mental foramen, giving rise to the mental nerve[1].

Due to its anatomical location, the IAN is at risk during various dental and surgical procedures. Injuries to this nerve can lead to temporary or permanent sensory disturbances, such as paresthesia or numbness. This article aims to educate patients by analyzing 100 clinical cases and providing insight into the anatomical, procedural, and outcome-related aspects of the IAN.

IAN courses in the canal to supply somatic afferent fibres to the gingiva anterior to the premolar, lip and chin. Detailed knowledge of the position, course and morphology of the mandibular canal is of utmost importance for performing various surgical procedures such as dental implant placement, periapical surgery, osteotomies, bone graft harvesting, bone plating procedures and administration of local anaesthesia.[2] During embryonic development and maturation, three IANs fuse to form a single nerve.[3] As a result of the abnormal interaction of tissues during embryonic development, the morphological alteration of the mandibular canal occurs.

In some cases, IAN runs inferior to the lower margin of the mental foramen. After giving off the incisive branch, it curves superiorly, turns posteriorly and reaches the mental foramen to continue as the mental nerve. The part of the mental nerve anterior to the mental foramen caused by this altered course of the IAN is called the mental nerve loop/anterior loop of the mental nerve[4-5].

MATERIALS AND METHODS

This is observational study of 100 patients was conducted at Daswani Dental College & Research Centre, Kota for 01 Year. Data was collected on:

  • Demographics
  • Type of dental procedure performed
  • Imaging modality used
  • Incidence of IAN-related symptoms
  • Management and recovery timeline

 

Inclusion Criteria:

  • Patients aged 18–70
  • Underwent procedures involving the lower jaw (extractions, implants, or nerve blocks)
  • Provided informed consent
  • Mandible fixation was included

 

Exclusion Criteria:

  • History of facial trauma was excluded
  • Pre-existing neurological disorders
  • Incomplete records.
RESULTS

Table 1: Demographics of Patients

Parameter

Value

Total Patients

100

Age Range

18–70 years

Average Age

38.4 years

Gender (M/F)

54 Male / 46 Female

 

Table 2: Procedures Performed

Procedure Type

Number of Patients (n=100)

Lower Third Molar Extraction

35

Dental Implant Placement

25

Inferior Alveolar Nerve Block

20

Root Canal Therapy (Molars)

10

Mandibular Fracture Fixation

05

Other (Biopsies, Lesion Removal)

05

 

Table 3: Incidence of IAN-Related Symptoms

Symptom

Number of Cases

% of Total

Transient Numbness (<2 weeks)

12

12%

Persistent Numbness (>2 weeks)

06

6%

Tingling/Burning Sensation

04

4%

Total IAN Involvement

22

22%

 

Transient Numbness (<2 weeks): 12 cases were reported, accounting for 12% of the total study population. This indicates short-term sensory loss that resolved within two weeks.

Persistent Numbness (>2 weeks): 6 cases, making up 6% of the total. These cases experienced numbness that lasted longer than two weeks, suggesting more prolonged or possibly permanent nerve involvement.

Tingling/Burning Sensation: Reported in 4 cases (4%), reflecting altered or uncomfortable nerve sensations without full numbness, commonly known as paresthesia or dysesthesia.

Total IAN Involvement: Overall, 22 cases (22% of the total population) showed some form of IAN-related symptom, whether transient or persistent.

 

Table 4: Imaging Used

Imaging Type

Patients (%)

Panoramic X-ray (OPG)

80

Cone Beam CT (CBCT)

40

Periapical Radiograph

35

 

Panoramic X-rays were the most frequently used imaging modality, followed by CBCT and periapical radiographs. The data suggest that while broad screening with panoramic imaging was standard, more detailed or focused imaging was used selectively based on clinical need.

 

Table 5: Recovery Timeline

Duration to Recovery

Patients (%)

< 1 Week

08

1–4 Weeks

10

1–3 Months

03

> 3 Months / Not Recovered

01

 

The majority of patients (18 out of 22, or 82%) recovered within four weeks. A small number experienced prolonged symptoms, and only one patient showed signs of long-term or unresolved nerve issues. The data suggests that while IAN symptoms are relatively common, they are typically temporary.

DISCUSSION

The IAN’s proximity to the roots of the mandibular molars and the implant osteotomy sites makes it highly vulnerable during surgical procedures. A thorough understanding of its course is essential to avoid complications[6-9].

Symptom Incidence: In this cohort, 22% of patients reported IAN-related symptoms postoperatively. The majority experienced temporary numbness or paresthesia, resolving within one month.

Use of CBCT helped in precisely locating the mandibular canal in high-risk cases, such as implants and third molar surgery. The use of panoramic radiography alone may underestimate nerve proximity, leading to avoidable complications[10-13].

Most IAN disturbances were transient, consistent with literature stating that 90% of injuries resolve spontaneously. Persistent symptoms in 1% of cases were referred for microsurgical consultation.

Patients often underestimate the risk of nerve injury. Clear pre-operative counseling and informed consent are essential, especially for high-risk procedures[14-16]. The IAN has shown to have morphological differences before entering the mandibular canal, as well as during its path within the mandibular canal. Significant variations are found in canal morphology. The most commonly discussed variations are the bifid canal, accessory canal, alteration in canal course and number of foramina at entry and exit of IAN.[17] As previously stated by Pyun et al., in 2013, these supplementary communications may supply additional innervation to the mandibular teeth and adjacent soft tissues and may be involved in inadequate dental anaesthesia due to the possibility for nerve impulse collateral transmission.[18].

CONCLUSION

The Inferior Alveolar Nerve is vital for the sensory innervation of the lower face and is at risk during many common dental procedures. In this study of 100 patients:

  • 22% experienced IAN-related symptoms
  • Most cases were mild and resolved within weeks
  • CBCT imaging significantly enhanced procedural safety

Patient awareness and dentist vigilance are critical in reducing nerve injury risk. This article serves as both a clinical resource and educational tool for patients and professionals.

REFERENCES
  1. Renton, T., Yilmaz, Z. (2011). Inferior alveolar nerve injury in relation to dental procedures: A review. British Dental Journal, 210(7), 377–382.
  2. Pogrel, M. A., et al. (2003). Permanent nerve involvement resulting from inferior alveolar nerve blocks. Journal of the American Dental Association, 134(4), 445–449.
  3. Greenstein, G., Tarnow, D. (2006). The mental foramen and nerve: Clinical and anatomical factors related to dental implant placement: A literature review. Journal of Periodontology, 77(12), 1933–1943.
  4. Auluck, A., Pai, K. M. (2005). Clinical anatomy of inferior alveolar nerve for implant surgery. Indian Journal of Dental Research, 16(4), 135–139.
  5. Ngeow, W. C., Yuzawati, Y. (2003). The location of the mental foramen in a selected Malay population. Journal of Oral Science, 45(3), 171–175.
  6. Kushnerev E, Yates JM. Evidence-based outcomes following inferior alveolar and lingual nerve injury and repair: a systematic review. J Oral Rehabil. 2015 Oct;42(10):786-802. 
  7. Joo W, Yoshioka F, Funaki T, Mizokami K, Rhoton AL. Microsurgical anatomy of the trigeminal nerve. Clin Anat. 2014 Jan;27(1):61-88. 
  8. Juodzbalys G, Wang HL, Sabalys G. Injury of the Inferior Alveolar Nerve during Implant Placement: a Literature Review. J Oral Maxillofac Res. 2011;2(1):e1. 
  9. Agbaje JO, Salem AS, Lambrichts I, Jacobs R, Politis C. Systematic review of the incidence of inferior alveolar nerve injury in bilateral sagittal split osteotomy and the assessment of neurosensory disturbances. Int J Oral Maxillofac Surg. 2015 Apr;44(4):447-51. 
  10. Pogrel MA, Thamby S. Permanent nerve involvement resulting from inferior alveolar nerve blocks. J Am Dent Assoc. 2000 Jul;131(7):901-7.
  11. Aquilanti L, Mascitti M, Togni L, Contaldo M, Rappelli G, Santarelli A. A Systematic Review on Nerve-Related Adverse Effects following Mandibular Nerve Block Anesthesia. Int J Environ Res Public Health. 2022 Jan 31;19(3) 
  12. Guerrero ME, Nackaerts O, Beinsberger J, Horner K, Schoenaers J, Jacobs R., SEDENTEXCT Project Consortium. Inferior alveolar nerve sensory disturbance after impacted mandibular third molar evaluation using cone beam computed tomography and panoramic radiography: a pilot study. J Oral Maxillofac Surg. 2012 Oct;70(10):2264-70. 
  13. Poort LJ, van Neck JW, van der Wal KG. Sensory testing of inferior alveolar nerve injuries: a review of methods used in prospective studies. J Oral Maxillofac Surg. 2009 Feb;67(2):292-300. 
  14. Graff-Radford SB, Evans RW. Lingual nerve injury. Headache. 2003 Oct;43(9):975-83. 
  15. Seddon HJ. A Classification of Nerve Injuries. Br Med J. 1942 Aug 29;2(4260):237-9.
  16. Sunderland S. The anatomy and physiology of nerve injury. Muscle Nerve. 1990 Sep;13(9):771-84. 
  17. Ziccardi VB, Assael LA. Mechanisms of trigeminal nerve injuries. Atlas Oral Maxillofac Surg Clin North Am. 2001 Sep;9(2):1-11. 
  18. Sullivan FM, Swan IR, Donnan PT, Morrison JM, Smith BH, McKinstry B, Davenport RJ, Vale LD, Clarkson JE, Hammersley V, Hayavi S, McAteer A, Stewart K, Daly F. Early treatment with prednisolone or acyclovir in Bell's palsy. N Engl J Med. 2007 Oct 18;357(16):1598-607.
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