Sanjeev Palta MD, Kanwaljit S. Gill MD, Ramdas G. Pai MD |
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Background and aim of the study: Mitral regurgitation (MR) is frequent in patients with severe calcific aortic stenosis (AS). This complicates not only the clinical course of AS, but also its surgical management. The aim of the present study was to investigate the mechanism of genesis of MR in patients with severe AS. |
(40 ± 16 versus 58 ± 18%; p = 0.0001), higher degree of aortic regurgitation (p = 0.002), larger left atrial diameter (4.7 ± 0.9 versus 4.1 ± 0.6 cm; p = 0.001), lower LV free wall thickness (1.1 ± 0.2 versus 1.3 ± 0.4 cm; p = 0.05), and lower combined wall thickness (2.4 ± 0.3 versus 2.7 ± 0.5 cm; p = 0.02) and relative wall thickness (0.5 ± 0.1 versus 0.6 ± 0.1 cm; p = 0.02). Both groups had similar degrees of AS and mitral annular calcification. |
Role of Inadequate Adaptive Left Ventricular Hypertrophy in the Genesis of Mitral Regurgitation in Patients with Severe Aortic Stenosis: Implications for its Prevention |
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